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PERSPECTIVE
Market Structure And Drug Innovation
Fabio Pammolli and
Massimo Riccaboni
An explosion of knowledge and a growing array of tools and technologies have transformed modern drug R&D, while its cost has risen by a sizable amount. At the same time, the unchecked increase in health care and prescription drug spending has spawned cost containment policies that are restricting the demand for drugs in all major markets. This Perspective explores the interplay between technological advances and regulatory policies and their likely impact on the dynamics of the pharmaceutical industry.

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J. H. Barton and E. J. Emanuel
The Patents-Based Pharmaceutical Development Process: Rationale, Problems, and Potential Reforms
JAMA,
October 26, 2005;
294(16):
2075 - 2082.
[Abstract]
[Full Text]
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