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PERSPECTIVE
Encouraging The Development Of New Vaccines
Henry Grabowski
Investment in the development of new vaccines is suboptimal. Changing this situation requires a creative blend of "push" and "pull" strategies. One successful policy model is the Orphan Drug Act, whose key features include large research and development (R&D) tax credits as well as Food and Drug Administration (FDA) counseling and priority review. Such supply-side R&D incentive provisions can be combined with demand-side mandates and vouchers to encourage development of new vaccines. Guaranteed-purchase funds and other pull mechanisms are useful supplementary incentives in the cases of vaccines for bioterrorism and neglected diseases of poverty.

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D. B. Ridley, H. G. Grabowski, and J. L. Moe
Developing drugs for developing countries.
Health Aff.,
March 1, 2006;
25(2):
313 - 324.
[Abstract]
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