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Health Affairs, 24, no. 3 (2005): 718-728
doi: 10.1377/hlthaff.24.3.718
© 2005 by Project HOPE
 
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* Vaccines

Implementation

Development Of Priority Vaccines For Disease-Endemic Countries: Risk And Benefit

Julie Milstien, Richard A. Cash, John Wecker and Daniel Wikler

Decisions regarding vaccine regulation and use made by institutions in industrialized countries can have an unintended impact on vaccines’ availability in disease-endemic countries. However, regulatory and programmatic decision making by such countries, taking into consideration local risks and benefits, requires adequate resources, both human and financial. Such differing risk-benefit determinations between industrialized and disease-endemic countries will increase product divergence. We propose a single universal standard for risk assessment, based on maximizing net benefit, and an action plan to improve access to priority vaccines through a more robust determination of risk and benefit.


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