Health Affairs, 25, no. 2 (2006): 325-336 doi: 10.1377/hlthaff.25.2.325 © 2006 by Project HOPE	New Online   May/June Issue: Health Reform Revisited   Reform and '08 Election   Promoting off-label drug use information

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Drugs/Vaccines

Will A Global Subsidy Of New Antimalarials Delay The Emergence Of Resistance And Save Lives?

Artemisinin-based combination treatments (ACTs) are seen as an important tool in the global effort to roll back malaria. With parasite resistance to chloroquine increasing rapidly in many parts of the world, there is greater recognition of the need for a globally coordinated strategy to ensure that artemisinins are not used as monotherapy, which has the potential to cut short their useful therapeutic life. We find that even a partial subsidy could delay the emergence of resistance and that a delay in implementing a subsidy for ACTs could facilitate the emergence of resistance and lower the economic value of ACTs.

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				H. Gelband and A. Seiter A Global Subsidy for Antimalarial Drugs Am J Trop Med Hyg, December 1, 2007; 77(6_Suppl): 219 - 221. [Abstract] [Full Text] [PDF]