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Health Affairs, 26, no. 3 (2007): 636-646
doi: 10.1377/hlthaff.26.3.636
© 2007 by Project HOPE
 
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Risks & Benefits

What’s More Dangerous, Your Aspirin Or Your Car? Thinking Rationally About Drug Risks (And Benefits)

Joshua T. Cohen and Peter J. Neumann

We compare mortality risks of several common drugs with risks related to work, transportation, and recreation. Comparing risks can provide a more intuitive sense of the magnitude of drug risks than stand-alone estimates can, to help inform policy discussions. The drug risks we quantify generally exceed the magnitude of risks for other domains (although aspirin and cars are similarly "risky" under the definition of risk used here). Nonetheless, these comparisons underscore a crucial point: that risks should not be evaluated without considering attendant benefits. We discuss the need for the Food and Drug Administration to compare risks and benefits quantitatively, consistently, and explicitly.


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Facts on Tysabri
David E. Kaplan
Health Affairs, 9 May 2007 [Full text]
Response To Tysabri Critique
Joshua T. Cohen, et al.
Health Affairs, 9 May 2007 [Full text]
Majority of the MS Community's Views on Tysabri
Lauren M. Roberts
Health Affairs, 10 May 2007 [Full text]
Valuable Statistics
Andrew H. White
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An Opportunity For Clarity
Harold Katlin
Health Affairs, 10 May 2007 [Full text]
Risks And Benefits Of Tysabri
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Health Affairs, 10 May 2007 [Full text]
Tysabri Reference In The Cohen/Neumann Paper
Chris Chan
Health Affairs, 10 May 2007 [Full text]
Root-Cause Failure Analysis Of Drug-Induced PML Morbidity
Mike Barron
Health Affairs, 14 May 2007 [Full text]


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