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CDC: HIV Prevention EffortsSystematic economic assessments such as the paper by Deborah Cohen and colleagues (Jul/Aug 05) richly inform policy development and affect resource allocation. To build on the tradition of similar work at the U.S. Centers for Disease Control and Prevention (CDC), a centralized prevention economics team was established in July 2005 within the CDCs Division of HIV/AIDS Prevention. We wish to clarify several points about the content and effectiveness of prevention activities supported by the CDC that the Cohen paper assessed incompletely and inaccurately. The initiative Advancing HIV Prevention (AHP) is an important focus at the CDC. Funding for this initiative, however, is a minority of the resources distributed by the CDC for HIV/AIDS prevention. The CDC supports a comprehensive approach to public health action designed to prevent HIV infections and minimize disability and death from this condition. A portfolio of funded interventions includes almost all of those identified as cost-effective. The exception: As noted by the authors, the CDC does not support needle exchange, because it is prohibited by federal law. The choice and calculation in the authors model created an incomplete evaluation of the CDCs prevention approach. Their outcome measure was "infections prevented." Indeed, decreasing the number of new HIV infections is a central goal of the CDC mission. But using a comprehensive measure such as the standard quality-adjusted life year (QALY) saved would have more thoroughly captured the beneficial effects of expanded testing programs that result from early diagnosis and treatment.1 In addition, the authors stated that the number of reported HIV diagnoses in 2002 was 26,000 cases, when the source document for these data clearly describes that the areas included in the analysis only cover about half of the HIV cases diagnosed in the United States.2 This specification error in the model, combined with an incomplete review of studies that demonstrate the effectiveness of interventions for HIV-positive people, resulted in greatly underestimating the overall potential benefit of partner counseling and referral, as well as prevention case management.
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